The best moisturizer to use with PanOxyl is True Botanicals Chebula Extreme Cream.
Since benzoyl peroxide products intended for acne-prone skin can be drying, the best moisturizer to use with PanOxyl needs nourishing ingredients like:
- Ceramides
- Cholesterol
- Essential fatty acids
- Glycerin and hyaluronic acid
These types of skin-loving ingredients will help protect your skin barrier and soothe signs of irritation like dryness.
Keep on reading to learn everything you need to know about PanOxyl and the best moisturizers to use with it.
Overview of Best Moisturizers for PanOxyl
Best Moisturizers to Use with PanOxyl
For a good moisturizer to use with PanOxyl, you want skincare products that won’t clog pores.
Best for Sensitive Skin: First Aid Beauty Ultra Repair Cream

First Aid Beauty
Ultra Repair Cream
Ultra Repair Cream is phenomenal for sensitive skin thanks to the 1% colloidal oatmeal in the formula.
The hyaluronic acid and sodium hyaluronate that attract moisture in the formula help keep skin hydrated too.
Best for Dry Skin: Substiane Riche Moisturizer
The best moisturizers for dry skin when you’re using benzoyl peroxide are heavy moisturizers!
Check out my La Roche Posay Creams Review as well.
Best Splurge Moisturizer: Triple Lipid Restore

SkinCeuticals
Triple Lipid Restore
One of the best moisturizers on the market in general is SkinCeuticals Triple Lipid Restore.
This stuff is fragrance-free and designed to mimic the natural oil your skin already produces.
It’ll moisturize and soothe irritation nicely.
In fact, Triple Lipid Restore is also one of the best moisturizers to use with tretinoin because its formula is nourishing!
What to Avoid in a Moisturizer if Using PanOxyl
If you’re using PanOxyl, you probably have acne prone skin. Therefore, I suggest being careful to avoid these ingredients because they’re known for clogging pores:
- Mineral oil
- Coconut oil
You’ll want a lightweight moisturizer if you deal with oily skin too.
PanOxyl Benzoyl Peroxide Wash

PanOxyl
4% Benzoyl Peroxide Wash
Studies show that benzoyl peroxide works in your skincare routine as a body wash or face wash by killing off acne-causing bacteria.
It’s a popular over-the-counter acne treatment because it’s affordable and fits into any skincare routine.
To make benzoyl peroxide work properly, you need the right moisturizer to go with it.
If you moisturize after you wash with benzoyl peroxide, you will:
- Protect your skin from irritation
- Treat acne
- Control excess oil production
- Get the smooth skin or clear skin you’re dreaming of
Learn more about How Benzoyl Peroxide Works.
PanOxyl 10% Benzoyl Peroxide

PanOxyl
10% Benzoyl Peroxide
Best for: body acne, acne-prone skin types, or oily skin
Take Caution: this might be too strong for your face and can cause irritated skin.
You May Also Like: a full protocol to get rid of back acne and hyperpigmentation.
PanOxyl 4% Benzoyl Peroxide

PanOxyl
4% Benzoyl Peroxide Wash
Best for: Oily skin, combination skin, sensitive skin
This is more gentle and can also be used as a face wash. I like this for oily skin or if you have excess oil on your face after exercising.
Paula’s Choice 2.5% Benzoyl Peroxide

Paula’s Choice
2.5% Benzoyl Peroxide
Best for: combination skin, dry skin, and sensitive skin
This is the gentle way to go with benzoyl peroxide in skin care.
It’ll leave more oil on your face and will still treat acne depending on the severity and your skin type.
You may also like my review of Best Paula’s Choice Products.
Frequently Asked Questions

Does benzoyl peroxide kill bacteria?
Yes! Benzoyl peroxide is one of the best active ingredients for acne prone skin and oily skin. Just pair it with a hydrating skincare routine to protect your moisture barrier.
Can benzoyl peroxide be a spot treatment?
Yes, you can use it to spot treat those pesky breakouts on your skin. I suggest getting a benzoyl peroxide gel for this instead of a creamy wash like PanOxyl though.
What are acne fighting alternatives to benzoyl peroxide?
Other active ingredients include:
- Salicylic acid: beta hydroxy acids help with new blemishes
- Azelaic acid: has anti-redness benefits like green tea in Korean skincare
- Adapalene: check out my Differin vs. La Roche Posay Adapalene Review
Salicylic acid can prevent breakouts with potentially less irritation than benzoyl peroxide depending on your skin type.
Also, adapalene helps clear out dead skin cells and smooth texture on the outer layer on your skin.
Salicylic acid treatments
CeraVe Renewing SA Cleanser

This cleanser is great for oily skin and acne prone skin.
Paula’s Choice 2% Skin Perfecting Liquid Exfoliant

This overnight exfoliant is great for acne prone skin, blackheads, and clogged pores.
Do I have to wear sunscreen if I use benzoyl peroxide?
It’s probably a good idea to use some level of sun protection factor in your skin care with benzoyl peroxide. SPF can also help prevent skin cancer and premature aging.

You’ll want to find a hydrating sunscreen that is non comedogenic. My favorite is this one from Elta MD.
Can you get benzoyl peroxide over the counter?
Yep! Similar to basic alpha hydroxy acids for example, you don’t need a prescription for PanOxyl.
There are some medications with benzoyl peroxide that you can get a prescription for though.
How often should I use PanOxyl?
As often as your skin can tolerate. Typically, 3-5 days per week is the sweet spot.
For people with oiler skin, you may be able to tolerate 6-7 days per week.
What kind of acne is PanOxyl good for?
PanOxyl will treat most acne except for severe cystic acne or fungal acne.